AT least twelve people were reported injured in a major fire that was burning in a four story building in the Bronx overnight, the second major blaze in the area in a week.
The flames broke out after 5am (9pm AEDT) in the Van Nest area of the Bronx in a building that houses a furniture store on the first floor and apartments on the upper floors.
Dozens of fire trucks were at the scene as thick smoke poured out of the building and flames were through the roof. Firefighters had been on the roof but they were evacuated.
Emergency services also had to contend with New York's brutally cold weather as they fought the flames. Temperatures were around -10C.
All of the residents of the building were believed to have been evacuated. There was no information about the conditions of the victims, although one person was reported to be in a critical condition.
That blaze started after a three-year-old boy was playing with a stove.
New York mayor Bill de Blasio described the incident as "the worst fire tragedy we have seen in this city in a quarter century".
"It will rank as one of the worst losses in a fire in many years.
"Based on the info now, I'm sorry to report 12 New Yorkers are dead, including one child. Four people are critically injured, fighting for their lives, and there are other serious injuries as well."
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